O2. DOSE REDUCTION IN NUCLEAR MEDICINE(PET-CT)
Positron Emission Tomography (PET) is one of the most used techniques for obtaining functional images in applications such as oncology, neurology and cardiology. Dosimetry in patients undergoing PET is of vital importance to ensure the safety of the procedure. All radiodiagnostic equipment (x-rays, mammography, CT, PET-CT and SEPT-CT) must have software capable of evaluating the dose received by the patient at the end of each diagnostic treatment. Therefore, it is essential to develop methods to estimate the doses received in internal organs due to the ionizing radiation imparted and to address how to reduce these doses.
The tasks involved are:
– Task 2.1. Development of internal dosimetry models from the GEANT-GATE and GEANT-GAMOS toolkits. The models include the PET scanner and mathematical and anthropomorphic phantoms, the latter obtained from the segmentation and voxelization of DICOM CT images.
– Task 2.2. Reconstruction of PET images from Monte Carlo simulations. Application to mathematical and anthropomorphic phantoms. Study of different reconstruction techniques. Fusion of dose maps and reconstructed images. Application to different clinical trials.
– Task 2.3. Comparison of the images generated by Monte Carlo with images from real clinical trials. Qualitative and quantitative characterization of errors between real and simulated images. Study of the possible assignment of the dose map obtained by simulation to real images.
– Task 2.4. Software validation with calibrated MOSFET detectors. Experimentally determine the dose delivered to dummies with the MOSFETs, and then, the comparison between the values calculated by Monte Carlo and the experimental dose
